Natural variation in linalool metabolites: One genetic locus, many functions?

Stromal Cell Derived Factor-1 Genetic Variation at Locus 801 in Patients with Myasthenia Gravis

Background: Myasthenia gravis (MG) is the most common disorder of neuromuscular junction in which autoantibodies develop against nicotinic acetylcholine receptor for unknown reasons. The association of immunomodulator genes with different autoimmune disease has been studied in recent years. Objective: The aim of this study was to investigate correlation between a genetic variation in Stromal Ce...

Calreticulin: one protein, one gene, many functions.

The endoplasmic reticulum (ER) plays a critical role in the synthesis and chaperoning of membrane-associated and secreted proteins. The membrane is also an important site of Ca(2+) storage and release. Calreticulin is a unique ER luminal resident protein. The protein affects many cellular functions, both in the ER lumen and outside of the ER environment. In the ER lumen, calreticulin performs t...

Fractalkine: one chemokine, many functions.

purification quality of CLP is important, especially for analyses of T-cell development. The original phenotypic CLP has recently been refined by addition of positivity for Flk25 and now a smaller population of cells including CD27 are shown to contain the T-cell potential. A specific criticism of the CLP as the thymus-seeding cell has been the lack of evidence that CLP can be detected in thymu...

The Many Entropies in One-Way Functions

Computational analogues of information-theoretic notions have given rise to some of the most interesting phenomena in the theory of computation. For example, computational indistinguishability, Goldwasser and Micali [9], which is the computational analogue of statistical distance, enabled the bypassing of Shanon’s impossibility results on perfectly secure encryption, and provided the basis for ...

Genetic variation in natural populations